5 Best Desktop Computers with Large RAM (2025)

This guide is written for those of you who run memory-intensive applications or workflows—from engineers simulating complex systems, to content creators handling 8K video editing, to developers spinning up multiple virtual machines. If your daily tasks stretch the limits of conventional computing, then you already know: RAM is a foundation.

The challenge lies in matching high RAM capacity with equally capable supporting hardware. You can’t just max out memory and expect magic. To actually benefit from large RAM configurations, your system needs high memory bandwidth, proper thermal planning, fast storage, and processors that can keep up with parallel tasks. This guide is built to help you select desktop PCs where large RAM capacity isn’t wasted.

We evaluate based on RAM capacity and bandwidth, CPU compatibility, motherboard architecture, cooling design, storage configuration, and scalability. Every system here comes equipped with 64GB RAM or higher, which we define as the threshold for large-memory computing.

Start with RAM capacity and bandwidth. 64GB to 256GB opens the door to advanced use cases. If you’re running multiple VMs, working with raw scientific data, managing architectural BIM models, or operating as a DAW power user, large memory pools allow uninterrupted multitasking. DDR5, with its higher frequency and lower power draw, gives better throughput in newer systems. For legacy compatibility, DDR4 still delivers solid reliability at 3200MHz or higher.

The CPU must match the memory capability. Intel’s Core i9 (13th/14th Gen), AMD Ryzen 9 7900X/7950X, and especially the Threadripper PRO series are designed for high-memory environments. They provide the memory controllers and thread counts needed to take advantage of 128GB, 192GB, or even 256GB of RAM. You’ll notice the difference in render queues, simulation runtimes, and the ability to switch between resource-hungry apps without stalling.

Motherboard architecture is another key. Systems designed for large RAM require chipsets with 4 or 8 DIMM slots, robust power delivery, and full support for XMP or EXPO memory profiles. A poorly designed board will throttle memory or cause instability at higher capacities. We recommend workstation-grade boards (Intel Z790, AMD X670E, WRX80) that can maintain full speed and voltage regulation across all modules.

Storage complements large RAM by handling scratch data, cache dumps, and high-speed read/writes. Every recommended system includes at least a 1TB NVMe SSD, with optional secondary SSDs or enterprise-grade HDDs. You can preload large data libraries, video timelines, simulation files, or development environments and still have room for live caching.

Scalability rounds out the list. As memory demands grow—through larger datasets, higher-resolution content, or more complex testing—you need headroom. Each system supports memory expansion, additional GPU installations, extra PCIe devices, and future CPU upgrades. This lets your investment remain viable for years, rather than aging out as software gets heavier.

All featured desktops include 64GB, 128GB, or 256GB of RAM, paired with multi-core CPUs, high-speed storage, and cooling systems that allow for sustained performance. They’re engineered for users who build, compute, simulate, or produce at scale.

This information helps you make the right purchasing decision when buying a PC with large RAM. You can also take a look at the best desktop computers with 32GB RAM in addition to the Best Desktop PCs with 16GB RAM.

These are the Best Desktop Computers with a Large RAM:

Skytech Gaming Azure PC Desktop – AMD Ryzen 7 7800X3D 4.2 GHz, NVIDIA RTX 4090, 1TB NVME Gen4 SSD, 32GB DDR5
See This On Amazon
CPU	AMD Ryzen 7 7800X3D
Processor Speed	4.2 GHz
GPU	NVIDIA RTX 4090
Graphics Card Memory	24 GB
RAM	32GB DDR5
Storage Space	1TB NVME Gen4 SSD
Operating System	Windows 11
Dimensions	26 x 24.7 x 14.55 inches
Keyboard & Mouse	Sold Separately
Computer Monitor	Sold Separately
Advantages	Performance
Disadvantages	Price

Skytech Gaming Prism Gaming PC, Ryzen 7 7800X3D 4.2 GHz, RTX 4070 Ti, 1TB NVME, 32GB DDR5
See This On Amazon
CPU	Ryzen 7 7800X3D
Processor Speed	4.2 GHz
GPU	RTX 4070 Ti
Graphics Card Memory	12 GB
RAM	32GB DDR5
Storage Space	1TB NVME
Operating System	Windows 11
Dimensions	‎23.4 x 22.9 x 15.9 inches
Keyboard & Mouse	Sold Separately
Computer Monitor	Sold Separately
Advantages	Performnce
Disadvantages	n/a

HP OMEN 45L Gaming Desktop, 13th Generation Intel Core i9-13900KF, 16 GB RAM, 1 TB Solid State Drive, NVIDIA GeForce RTX 4070 Ti
See This On Amazon
CPU	Intel Core i9-13900KF
Processor Speed	up to 5.80 GHz
GPU	NVIDIA GeForce RTX 4070 Ti
Graphics Card Memory	12GB
RAM	32 GB DDR5
Storage Space	‎1 TB 1 TB PCIe NVMe M.2 SSD
Operating System	Windows 11
Dimensions	8.03 x 18.5 x 21.85 inches
Keyboard & Mouse	Sold Separately
Computer Monitor	Sold Separately
Advantages	Low power use, Looks good, powerful
Disadvantages	Quite expensive

Alienware Aurora R16 Gaming Desktop - Intel Core i9-13900F, 32GB DDR5 RAM, 1TB SSD + 1TB HDD, NVIDIA GeForce RTX 4070
See This On Amazon
CPU	Intel Core i9-13900F
Processor Speed	5.6 GHz
GPU	NVIDIA GeForce RTX 4070
Graphics Card Memory	12GB GDDR6X
RAM	32GB DDR5
Storage Space	1TB SSD + 1TB HDD
Operating System	Windows 11
Dimensions	Compact
Keyboard & Mouse	Sold Separately
Computer Monitor	Sold Separately
Advantages	Very good performance, size
Disadvantages	Price

iBUYPOWER Y40 Black Gaming PC Computer Desktop Y40BA9R79XTX01 (Ryzen 9 7900x, RX 7900 XTX 24GB, 32GB
See This On Amazon
CPU	Ryzen 9 7900x
Processor Speed	‎3.7 GHz
GPU	RX 7900 XTX
Graphics Card Memory	24GB
RAM	32GB
Storage Space	2TB NVMe
Operating System	Windows 11
Dimensions	17.28 x 9.44 x 18.58 inches
Keyboard & Mouse	Included
Computer Monitor	Sold Separately
Advantages	Price, Value for money
Disadvantages	None

MORE DESKTOP PC RECOMMENDATIONS:

Best Desktop PCs with 64GB RAM

Latest Top 8GB RAM Desktop Computers

Top PCs with 4GB RAM

Best PC with both SSD and HDD